![]() ![]() NF‐κB signaling dynamics play a key role in infection control in tuberculosis. Relative importance of NF‐kappaB p50 in mycobacterial infection. ![]() Yamada H, Mizuno S, Reza‐Gholizadeh M, Sugawara I. Induction of pro‐inflammatory cytokines (IL‐1 and IL‐6) and lung inflammation by Coronavirus‐19 (COVI‐19 or SARS‐CoV‐2): anti‐inflammatory strategies. The determination of the perceived stress levels and health‐protective behaviors of nursing students during the COVID‐19 pandemic. Mycobacterium tuberculosis SARS-COV-2 pathogenesis prognosis tuberculin skin test.Įrsin F, Kartal M. TST positivity is favorably associated with the course of COVID-19. COVID-19 patients with positive TST showed a significantly higher rate of mild disease than those with negative TST. The maximum Youden J index value was 0.522 at an induration diameter of 6.5 mm, which had a sensitivity of 66.0% and specificity of 86.2%. The area under the receiver operating characteristic (ROC) curve of TST induration size for the differentiation of mild with moderate and severe disease was 0.768 (p < 0.001). Patients with mild disease had a significantly higher TST positivity rate (p < 0.001) and larger induration diameter (p < 0.001). All TST-positive patients had mild disease. ![]() COVID-19 severity was mild in 47 patients (61.8%), moderate in 22 patients (28.9%), and severe in seven patients (9.3%). Of the 76 patients, TST results were negative for 53 patients (69.7%) and positive for 23 patients (30.3%). Relationships between COVID-19 clinical severity and TST positivity, induration size, and other clinical parameters were analyzed. Of 1963 adult patients who underwent TST, 76 patients with SARS-COV-2 infection confirmed by RT-PCR analysis of respiratory tract samples were included in the study. This study investigated the relationship between tuberculin skin test (TST) induration diameter and the clinical course of COVID-19. As severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) has a similar pathogenetic pathway to Mycobacterium tuberculosis, it has been reported that there may be a relationship between Bacille Calmette-Guérin (BCG) vaccination rate and COVID-19 severity. The pathogenesis of coronavirus disease 2019 (COVID-19) is still not fully understood. ![]()
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